TY - JOUR
T1 - [Translated article] Biological Biomarkers in Respiratory Diseases
AU - García-Río, Francisco
AU - Alcázar-Navarrete, Bernardino
AU - Castillo-Villegas, Diego
AU - Cilloniz, Catia
AU - García-Ortega, Alberto
AU - Leiro-Fernández, Virginia
AU - Lojo-Rodriguez, Irene
AU - Padilla-Galo, Alicia
AU - Quezada-Loaiza, Carlos A.
AU - Rodriguez-Portal, Jose Antonio
AU - Sánchez-de-la-Torre, Manuel
AU - Sibila, Oriol
AU - Martínez-García, Miguel A.
N1 - Publisher Copyright:
© 2022 SEPAR
PY - 2022/4
Y1 - 2022/4
N2 - In recent years, personalized or precision medicine has made effective inroads into the management of diseases, including respiratory diseases. The route to implementing this approach must invariably start with the identification and validation of biological biomarkers that are closely related to the diagnosis, treatment, and prognosis of respiratory patients. In this respect, biological biomarkers of greater or lesser reliability have been identified for most respiratory diseases and disease classes, and a large number of studies are being conducted in the search for new indicators. The aim of this review is to update the reader and to analyze the existing scientific literature on the existence and diagnostic, therapeutic, and prognostic validity of the most important biological biomarkers in the main respiratory diseases, and to identify future challenges in this area.
AB - In recent years, personalized or precision medicine has made effective inroads into the management of diseases, including respiratory diseases. The route to implementing this approach must invariably start with the identification and validation of biological biomarkers that are closely related to the diagnosis, treatment, and prognosis of respiratory patients. In this respect, biological biomarkers of greater or lesser reliability have been identified for most respiratory diseases and disease classes, and a large number of studies are being conducted in the search for new indicators. The aim of this review is to update the reader and to analyze the existing scientific literature on the existence and diagnostic, therapeutic, and prognostic validity of the most important biological biomarkers in the main respiratory diseases, and to identify future challenges in this area.
KW - Asthma
KW - Biomarkers
KW - Bronchiectasis
KW - COPD
KW - Chronic obstructive pulmonary disease
KW - Cystic fibrosis
KW - Idiopathic pulmonary fibrosis
KW - Lung cancer
KW - Pleural effusion
KW - Pneumonia
KW - Pulmonary arterial hypertension
KW - Pulmonary embolism
KW - Respiratory disorders
KW - Sleep apnea
KW - Systemic disorders
UR - http://www.scopus.com/inward/record.url?scp=85147790033&partnerID=8YFLogxK
U2 - 10.1016/j.arbres.2022.01.010
DO - 10.1016/j.arbres.2022.01.010
M3 - Short survey
AN - SCOPUS:85147790033
SN - 0300-2896
VL - 58
SP - T323-T333
JO - Archivos de Bronconeumologia
JF - Archivos de Bronconeumologia
IS - 4
ER -