Riesgo de preeclampsia y suplementación de vitamina C y E: revisión sistemática y metanálisis

María Teresa Perdomo Rebaza; Víctor Juan Vera-Ponce; Jenny Raquel Torres-Malca; Jesus E. Talavera; Fiorella E. Zuzunaga-Montoya; Jhony A.De La Cruz-Vargas

Riesgo de preeclampsia y suplementación de vitamina C y E: revisión sistemática y metanálisis

María Teresa Perdomo Rebaza, Víctor Juan Vera-Ponce, Jenny Raquel Torres-Malca, Jesus E. Talavera, Fiorella E. Zuzunaga-Montoya, Jhony A.De La Cruz-Vargas

Producción científica: Artículo Científico › Artículo original › revisión exhaustiva

Resumen

Introduction: It has been suggested that preeclampsia can be prevented by vitamin E and C intake, given the pathophysiological mechanism of this disease. Objective: To determine the joint efficacy of vitamin C and E in the prevention of preeclampsia. Methods: Systematic review of randomized clinical trials. A search of pubmed/medline, SCOPUS, Web of Science, Cochrane Library, EMBASE, and Clinical Trials databases was performed. The risk of bias of the randomized clinical trials was assessed using the Cochrane tool version 2. A random-effects meta-analysis was performed and relative risks were calculated, with corresponding 95 % confidence intervals. Results: Seven studies were included (n= 1 475). No statistically significant association of treatment with vitamin C and E supplementation was found with respect to preeclampsia (relative risks: 1.03; 95 % CI 0.78-1.26). Conclusions: Dual vitamin C and E supplementation does not prevent preeclampsia in pregnant women at risk for the disease.

Título traducido de la contribución	Risk of preeclampsia and Vitamin C and E supplementation: a systematic review and meta-analysis
Idioma original	Español
-	e02202098
Publicación	Revista Cubana de Medicina Militar
Volumen	51
N.º	3
Estado	Indizado - 1 jul. 2022
Publicado de forma externa	Sí

Nota bibliográfica

Publisher Copyright:
© 2022, Editorial Ciencias Medicas. All rights reserved.

Palabras clave

disease prevention
pre-Eclampsia
vitamin C
vitamin E

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title = "Riesgo de preeclampsia y suplementaci{\'o}n de vitamina C y E: revisi{\'o}n sistem{\'a}tica y metan{\'a}lisis",

abstract = "Introduction: It has been suggested that preeclampsia can be prevented by vitamin E and C intake, given the pathophysiological mechanism of this disease. Objective: To determine the joint efficacy of vitamin C and E in the prevention of preeclampsia. Methods: Systematic review of randomized clinical trials. A search of pubmed/medline, SCOPUS, Web of Science, Cochrane Library, EMBASE, and Clinical Trials databases was performed. The risk of bias of the randomized clinical trials was assessed using the Cochrane tool version 2. A random-effects meta-analysis was performed and relative risks were calculated, with corresponding 95 % confidence intervals. Results: Seven studies were included (n= 1 475). No statistically significant association of treatment with vitamin C and E supplementation was found with respect to preeclampsia (relative risks: 1.03; 95 % CI 0.78-1.26). Conclusions: Dual vitamin C and E supplementation does not prevent preeclampsia in pregnant women at risk for the disease.",

keywords = "disease prevention, pre-Eclampsia, vitamin C, vitamin E",

author = "Rebaza, {Mar{\'i}a Teresa Perdomo} and Vera-Ponce, {V{\'i}ctor Juan} and Torres-Malca, {Jenny Raquel} and Talavera, {Jesus E.} and Zuzunaga-Montoya, {Fiorella E.} and Cruz-Vargas, {Jhony A.De La}",

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T1 - Riesgo de preeclampsia y suplementación de vitamina C y E

T2 - revisión sistemática y metanálisis

AU - Rebaza, María Teresa Perdomo

AU - Vera-Ponce, Víctor Juan

AU - Torres-Malca, Jenny Raquel

AU - Talavera, Jesus E.

AU - Zuzunaga-Montoya, Fiorella E.

AU - Cruz-Vargas, Jhony A.De La

PY - 2022/7/1

Y1 - 2022/7/1

N2 - Introduction: It has been suggested that preeclampsia can be prevented by vitamin E and C intake, given the pathophysiological mechanism of this disease. Objective: To determine the joint efficacy of vitamin C and E in the prevention of preeclampsia. Methods: Systematic review of randomized clinical trials. A search of pubmed/medline, SCOPUS, Web of Science, Cochrane Library, EMBASE, and Clinical Trials databases was performed. The risk of bias of the randomized clinical trials was assessed using the Cochrane tool version 2. A random-effects meta-analysis was performed and relative risks were calculated, with corresponding 95 % confidence intervals. Results: Seven studies were included (n= 1 475). No statistically significant association of treatment with vitamin C and E supplementation was found with respect to preeclampsia (relative risks: 1.03; 95 % CI 0.78-1.26). Conclusions: Dual vitamin C and E supplementation does not prevent preeclampsia in pregnant women at risk for the disease.

AB - Introduction: It has been suggested that preeclampsia can be prevented by vitamin E and C intake, given the pathophysiological mechanism of this disease. Objective: To determine the joint efficacy of vitamin C and E in the prevention of preeclampsia. Methods: Systematic review of randomized clinical trials. A search of pubmed/medline, SCOPUS, Web of Science, Cochrane Library, EMBASE, and Clinical Trials databases was performed. The risk of bias of the randomized clinical trials was assessed using the Cochrane tool version 2. A random-effects meta-analysis was performed and relative risks were calculated, with corresponding 95 % confidence intervals. Results: Seven studies were included (n= 1 475). No statistically significant association of treatment with vitamin C and E supplementation was found with respect to preeclampsia (relative risks: 1.03; 95 % CI 0.78-1.26). Conclusions: Dual vitamin C and E supplementation does not prevent preeclampsia in pregnant women at risk for the disease.

KW - disease prevention

KW - pre-Eclampsia

KW - vitamin C

KW - vitamin E

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M3 - Artículo original

AN - SCOPUS:85138414264

SN - 0138-6557

VL - 51

JO - Revista Cubana de Medicina Militar

JF - Revista Cubana de Medicina Militar

IS - 3

M1 - e02202098

ER -

Riesgo de preeclampsia y suplementación de vitamina C y E: revisión sistemática y metanálisis

Resumen

Nota bibliográfica

Palabras clave

Huella

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