Pneumonia

Antoni Torres, Catia Cilloniz, Michael S. Niederman, Rosario Menéndez, James D. Chalmers, Richard G. Wunderink, Tom van der Poll

Producción científica: Artículo CientíficoArtículo de revisiónrevisión exhaustiva

198 Citas (Scopus)

Resumen

Pneumonia is a common acute respiratory infection that affects the alveoli and distal airways; it is a major health problem and associated with high morbidity and short-term and long-term mortality in all age groups worldwide. Pneumonia is broadly divided into community-acquired pneumonia or hospital-acquired pneumonia. A large variety of microorganisms can cause pneumonia, including bacteria, respiratory viruses and fungi, and there are great geographical variations in their prevalence. Pneumonia occurs more commonly in susceptible individuals, including children of <5 years of age and older adults with prior chronic conditions. Development of the disease largely depends on the host immune response, with pathogen characteristics having a less prominent role. Individuals with pneumonia often present with respiratory and systemic symptoms, and diagnosis is based on both clinical presentation and radiological findings. It is crucial to identify the causative pathogens, as delayed and inadequate antimicrobial therapy can lead to poor outcomes. New antibiotic and non-antibiotic therapies, in addition to rapid and accurate diagnostic tests that can detect pathogens and antibiotic resistance will improve the management of pneumonia.

Idioma originalInglés estadounidense
-25
PublicaciónNature Reviews Disease Primers
Volumen7
N.º1
DOI
EstadoIndizado - dic. 2021
Publicado de forma externa

Nota bibliográfica

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© 2021, Springer Nature Limited.

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