TY - JOUR
T1 - Green synthesis of spinel copper ferrite (CuFe2O4) nanoparticles and their toxicity
AU - Jasim, Saade Abdalkareem
AU - Patra, Indrajit
AU - Opulencia, Maria Jade Catalan
AU - Hachem, Kadda
AU - Parra, Rosario Mireya Romero
AU - Ansari, Mohammad Javed
AU - Jalil, Abduladheem Turki
AU - Al-Gazally, Moaed E.
AU - Naderifar, Mahin
AU - Khatami, Mehrdad
AU - Akhavan-Sigari, Reza
N1 - Funding Information:
Funding information: This work was supported by Tarbiat Modares University.
Publisher Copyright:
© 2022 Saade Abdalkareem Jasim et al., published by De Gruyter.
PY - 2022/1/1
Y1 - 2022/1/1
N2 - In this study, magnetic spinel copper ferrite (CuFe2O4) nanostructures were eco-friendly synthesized using Nasturtium officinale extract. Physicochemical properties of these nanostructures were determined by transmission electron microscopy, field emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD), vibrating sample magnetometry, and energy dispersive X-ray mapping analysis. XRD patterns conform to the CuFe2O4 formation. SEM results demonstrated ceramic spinel CuFe2O4 nanostructures with spherical surface morphologies. The cytotoxicity effect of CuFe2O4 nanostructures against rat pheochromocytoma (PC12) cells was evaluated based on MTT assay. The magnetic nanostructures had low toxicity at a concentration of 250 μg/mL. It appears that these nanostructures can be considered as suitable candidates for drug delivery and other biomedical applications, because of their low toxicity effects.
AB - In this study, magnetic spinel copper ferrite (CuFe2O4) nanostructures were eco-friendly synthesized using Nasturtium officinale extract. Physicochemical properties of these nanostructures were determined by transmission electron microscopy, field emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD), vibrating sample magnetometry, and energy dispersive X-ray mapping analysis. XRD patterns conform to the CuFe2O4 formation. SEM results demonstrated ceramic spinel CuFe2O4 nanostructures with spherical surface morphologies. The cytotoxicity effect of CuFe2O4 nanostructures against rat pheochromocytoma (PC12) cells was evaluated based on MTT assay. The magnetic nanostructures had low toxicity at a concentration of 250 μg/mL. It appears that these nanostructures can be considered as suitable candidates for drug delivery and other biomedical applications, because of their low toxicity effects.
KW - copper ferrite nanostructures
KW - cytotoxicity evaluation
KW - green chemistry
KW - magnetic ceramic ferrites
KW - plant extracts
UR - http://www.scopus.com/inward/record.url?scp=85133534363&partnerID=8YFLogxK
U2 - 10.1515/ntrev-2022-0143
DO - 10.1515/ntrev-2022-0143
M3 - Original Article
AN - SCOPUS:85133534363
SN - 2191-9089
VL - 11
SP - 2483
EP - 2492
JO - Nanotechnology Reviews
JF - Nanotechnology Reviews
IS - 1
ER -