Genetic variants and source of introduction of SARS-CoV-2 in South America

Julio A. Poterico, Orson Mestanza

Producción científica: Artículo CientíficoArtículo originalrevisión exhaustiva

30 Citas (Scopus)


After more than 4 months of the COVID-19 pandemics with genomic information of SARS-CoV-2 around the globe, there are more than 1000 complete genomes of this virus. We used 691 genomes from the GISAID database. Several studies have been reporting mutations and hotspots according to viral evolution. Our work intends to show and compare positions that have variants in 30 complete viral genomes from South American countries. We classified strains according to point alterations and portray the source where strains came into this region. Most viruses entered South America from Europe, followed by Oceania. Only Chilean isolates demonstrated a relationship with Asian isolates. Some changes in South American genomes are near to specific domains related to viral replication or the S protein. Our work contributes to the global understanding of which sort of strains are spreading throughout South America, and the differences among them according to the first isolates introduced to this region.

Idioma originalInglés estadounidense
Páginas (desde-hasta)2139-2145
PublicaciónJournal of Medical Virology
EstadoIndizado - 1 oct. 2020
Publicado de forma externa

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© 2020 Wiley Periodicals LLC


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