Epigenética: la relación del medio ambiente con el genoma y su influencia en la salud mental

Sandro Casavilca-Zambrano, Karina Cancino-Maldonado, Luis Jaramillo-Valverde, Heinner Guio

Producción científica: Artículo CientíficoArtículo de revisiónrevisión exhaustiva

2 Citas (Scopus)

Resumen

The study of the human genome, when performed only through the DNA sequence information, does not completely explain the high level of inter-individual variation usually observed. It is the control of gene expression by the epigenetics what allows to explain those variations of gene expression, as a reversible and hereditary process in the short term under the influence of the environment during various stages of development and adulthood, without modifying the genetic sequence. Epigenetic alterations are already being studied as valuable candidates in the eventual identification of biomarkers. Furthermore, their reversible nature makes them promising factors in the amelioration of disease symptoms through the use of therapeutic approaches. This article explains the epigenetic mechanisms and its relationship with the environment, diet, and its influence on evolution, the occurrence of diseases, human behavior and mental health.

Título traducido de la contribuciónEpigenetics: The relationship of the environment and mental health
Idioma originalEspañol
Páginas (desde-hasta)266-273
-8
PublicaciónRevista de Neuro-Psiquiatria
Volumen82
N.º4
DOI
EstadoIndizado - oct. 2019
Publicado de forma externa

Nota bibliográfica

Publisher Copyright:
© 2019 Universidad Peruana Cayetano Heredia, Facultad de Medicina Alberto Hurtado. All rights reserved.

Palabras clave

  • Epigenetics
  • environment
  • evolution
  • gene expression
  • mental health

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