TY - JOUR
T1 - Cutaneous Manifestations of Zika in Peru
AU - Ramos, Willy
AU - Luna, Miguel
AU - Alarcón, Tania
AU - Jiménez, Gerardo
AU - Díaz, Jesús
AU - Calderón, María
AU - Gutierrez, Ericson L.
N1 - Funding Information:
The authors wish to thank Mohamed Akl for the critical review of this article. The present manuscript is exclusive responsibility of the authors and does not represent an official opinion of the Ministry of Health of Peru, the Regional Health Department of Ica or the National Institute of Health of Peru. The author(s) received no financial support for the research, authorship, and/or publication of this article.
Publisher Copyright:
© The Author(s) 2019.
PY - 2020/1/1
Y1 - 2020/1/1
N2 - This article aims to describe the cutaneous manifestations observed in the Zika epidemic in Peru during 2016 and 2017, as well as discuss the potential differential diagnoses. During the outbreak, the main reason for seeking medical advice was the development of a pruriginous maculopapular rash with a marked papular component, which started on the chest and later generalized to the rest of the body. Similar manifestations were noted in adults, children, and pregnant women. Other manifestations such as conjunctivitis, edema, or petechiae on the palate were rare. We suggest that in areas that are endemic for arboviral infections, in the differential diagnosis of a rash one must consider infections such as dengue, Zika, or chikungunya viruses. In nonendemic areas, the diagnosis is more difficult, as the rash may result from other viral infections not transmitted by arthropods and/or reactive or inflammatory diseases (urticaria, atopic dermatitis, systemic lupus erythematosus). We recommend that primary care health personnel are trained in the recognition of the mucocutaneous lesions caused by Zika virus infection, which could contribute to the identification of suspicious cases, particularly pregnant women.
AB - This article aims to describe the cutaneous manifestations observed in the Zika epidemic in Peru during 2016 and 2017, as well as discuss the potential differential diagnoses. During the outbreak, the main reason for seeking medical advice was the development of a pruriginous maculopapular rash with a marked papular component, which started on the chest and later generalized to the rest of the body. Similar manifestations were noted in adults, children, and pregnant women. Other manifestations such as conjunctivitis, edema, or petechiae on the palate were rare. We suggest that in areas that are endemic for arboviral infections, in the differential diagnosis of a rash one must consider infections such as dengue, Zika, or chikungunya viruses. In nonendemic areas, the diagnosis is more difficult, as the rash may result from other viral infections not transmitted by arthropods and/or reactive or inflammatory diseases (urticaria, atopic dermatitis, systemic lupus erythematosus). We recommend that primary care health personnel are trained in the recognition of the mucocutaneous lesions caused by Zika virus infection, which could contribute to the identification of suspicious cases, particularly pregnant women.
KW - Peru
KW - Zika virus infection
KW - arboviruses
KW - skin rash
UR - http://www.scopus.com/inward/record.url?scp=85074039367&partnerID=8YFLogxK
U2 - 10.1177/1203475419878160
DO - 10.1177/1203475419878160
M3 - Original Article
C2 - 31556723
AN - SCOPUS:85074039367
SN - 1203-4754
VL - 24
SP - 33
EP - 40
JO - Journal of Cutaneous Medicine and Surgery
JF - Journal of Cutaneous Medicine and Surgery
IS - 1
ER -