TY - JOUR
T1 - Community-acquired pneumonia in critically ill very old patients
T2 - A growing problem
AU - Cillóniz, Catia
AU - Dominedò, Cristina
AU - Pericàs, Juan M.
AU - Rodriguez-Hurtado, Diana
AU - Torres, Antoni
N1 - Funding Information:
Support statement: Publication was funded by Ciber de Enfermedades Respiratorias (CibeRes CB06/06/0028) and the 2009 Support to Research Groups in Catalonia 911, IDIBAPS (CERCA Programme/Generalitat de Catalunya). C. Cillóniz is the recipient of a postdoctoral grant (Strategic Plan for Research and Innovation in Health-PERIS 2016–2020), SEPAR fellowship 2008 and the Fondo de Investigación Sanitaria (grant PI19/00207). Funding information for this article has been deposited with the Crossref Funder Registry.
Publisher Copyright:
© ERS 2020.
PY - 2020/3
Y1 - 2020/3
N2 - Very old (aged ≥80 years) adults constitute an increasing proportion of the global population. Currently, this subgroup of patients represents an important percentage of patients admitted to the intensive care unit. Community-acquired pneumonia (CAP) frequently affects very old adults. However, there are no specific recommendations for the management of critically ill very old CAP patients. Multiple morbidities, polypharmacy, immunosenescence and frailty contribute to an increased risk of pneumonia in this population. CAP in critically ill very old patients is associated with higher short-and long-term mortality; however, because of its uncommon presentation, diagnosis can be very difficult. Management of critically ill very old CAP patients should be guided by their baseline characteristics, clinical presentation and risk factors for multidrug-resistant pathogens. Hospitalisation in intermediate care may be a good option for critical ill very old CAP patients who do not require invasive procedures and for whom intensive care is questionable in terms of benefit.
AB - Very old (aged ≥80 years) adults constitute an increasing proportion of the global population. Currently, this subgroup of patients represents an important percentage of patients admitted to the intensive care unit. Community-acquired pneumonia (CAP) frequently affects very old adults. However, there are no specific recommendations for the management of critically ill very old CAP patients. Multiple morbidities, polypharmacy, immunosenescence and frailty contribute to an increased risk of pneumonia in this population. CAP in critically ill very old patients is associated with higher short-and long-term mortality; however, because of its uncommon presentation, diagnosis can be very difficult. Management of critically ill very old CAP patients should be guided by their baseline characteristics, clinical presentation and risk factors for multidrug-resistant pathogens. Hospitalisation in intermediate care may be a good option for critical ill very old CAP patients who do not require invasive procedures and for whom intensive care is questionable in terms of benefit.
UR - http://www.scopus.com/inward/record.url?scp=85079786362&partnerID=8YFLogxK
U2 - 10.1183/16000617.0126-2019
DO - 10.1183/16000617.0126-2019
M3 - Review article
C2 - 32075858
AN - SCOPUS:85079786362
SN - 0905-9180
VL - 29
JO - European Respiratory Review
JF - European Respiratory Review
IS - 155
M1 - 190126
ER -