Role of mHealth in overcoming the occurrence of post-stroke depression

J. J. Miranda, M. G. Moscoso, M. Toyama, V. Cavero, F. Diez-Canseco, B. Ovbiagele

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations


Depression associated with stroke affects roughly one-third of stroke survivors. Post-stroke depression (PSD) is thought to adversely influence functional outcome by limiting participation in rehabilitation, decreasing physical, social, and cognitive function, and affecting neuroplasticity thereby placing stroke survivors at high risk for future vascular events. PSD has also been associated with higher mortality rates after stroke. In Peru, a country where there is no national stroke program and mental health disorders are largely underdiagnosed and untreated, people with PSD are likely to be further challenged by dependency and impoverished conditions that will limit their use of ambulatory services, leading to inadequate clinical follow-up. In this scenario, mobile health (mHealth) technology offers a promising approach to extend access to high-quality and culturally tailored evidence-based psychological care to address PSD given that cell phone use, Internet connectivity, and digital health technology have met a rapid growth in the last years and thus contribute to the attainment of broader Sustainable Development Goals (SDGs). The limited evidence of the effectiveness of mHealth for PSD calls for researchers to fill a knowledge gap where Peru poses as an ideal setting because rapid expansion of digital technology and current mental healthcare reform could be leveraged to enhance post-stroke outcomes. This article proposes the rationale for a suitable evidence-driven, mHealth-based, PSD self-management intervention called iMOODS—Investigating the role of mHealth in overcoming occurrence of depression after stroke—that could be tested among recent stroke patients with PSD in resource constrained settings.

Original languageAmerican English
Pages (from-to)12-19
Number of pages8
JournalActa Neurologica Scandinavica
Issue number1
StateIndexed - Jan 2018
Externally publishedYes

Bibliographical note

Funding Information:
JJM acknowledges receiving current and past support from the Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica (CONCYTEC), DFID/MRC/Wellcome Global Health Trials (MR/M007405/1), Fogarty International Center (R21TW009982), Grand Challenges Canada (0335-04), International Development Research Center Canada (106887, 108167), Inter-American Institute for Global Change Research (IAI CRN3036), National Heart, Lung and Blood Institute (5U01HL114180, HHSN268200900028C), National Institute of Mental Health (1U19MH098780), Swiss National Science Foundation (40P740-160366), Universidad Peruana Cayetano Heredia, and the Wellcome Trust (074833/Z/04/A, WT093541AIA, 103994/Z/14/Z). Dr Ovbiagele is supported by National Institutes of Neurological Disorders and Stroke (R21NS094033).

Publisher Copyright:
© 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd


  • depression
  • implementation
  • mHealth
  • stroke


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