Recent advances in vaccine and immunotherapy for COVID-19

Ali A. Rabaan, Shamsah H. Al-Ahmed, Ranjit Sah, Jaffar A. Al-Tawfiq, Ayman M. Al-Qaaneh, Lamiaa H. Al-Jamea, Alexander Woodman, Manaf Al-Qahtani, Shafiul Haque, Harapan Harapan, D. Katterine Bonilla-Aldana, Pavan Kumar, Kuldeep Dhama, Alfonso J. Rodriguez-Morales

Research output: Contribution to journalOriginal Articlepeer-review

31 Scopus citations

Abstract

The COVID-19 pandemic caused by SARS-CoV-2 has resulted in millions of cases and hundreds of thousands of deaths. Beyond there being no available antiviral therapy, stimulating protective immunity by vaccines is the best option for managing future infections. Development of a vaccine for a novel virus is a challenging effort that may take several years to accomplish. This mini-review summarizes the immunopathological responses to SARS-CoV-2 infection and discusses advances in the development of vaccines and immunotherapeutics for COVID-19.

Original languageAmerican English
Pages (from-to)3011-3022
Number of pages12
JournalHuman Vaccines and Immunotherapeutics
Volume16
Issue number12
DOIs
StateIndexed - 2020
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2020 The Author(s). Published with license by Taylor & Francis Group, LLC.

Keywords

  • COVID-19
  • SARS-CoV-2
  • immunotherapeutics
  • pandemic
  • vaccine

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