Human hydatid disease in Peru is basically restricted to Echinococcus granulosus genotype G1

Saul J. Santivañez; Ariana M. Gutierrez; Mara C. Rosenzvit; Patricia M. Muzulin; Mary L. Rodriguez; Julio C. Vasquez; Silvia Rodriguez; Armando E. Gonzalez; Robert H. Gilman; Hector H. Garcia

doi:10.4269/ajtmh.2008.79.89

Human hydatid disease in Peru is basically restricted to Echinococcus granulosus genotype G1

Saul J. Santivañez, Ariana M. Gutierrez, Mara C. Rosenzvit, Patricia M. Muzulin, Mary L. Rodriguez, Julio C. Vasquez, Silvia Rodriguez, Armando E. Gonzalez, Robert H. Gilman, Hector H. Garcia

Research output: Contribution to journal › Original Article › peer-review

26 Scopus citations

Abstract

A molecular PCR study using DNA from 21 hydatid cysts was performed to determine which strain type is responsible for human infection in Peru. The mitochondrial cytochrome c oxidase subunit 1 (CO1) gene was amplified in 20 out of 21 samples, revealing that all but 1 sample (19/20, 95%) belonged to the common sheep strain (G1). The remaining samples belonged to the camel strain (G6). The G1 genotype was most frequently found in human cases of cystic hydatid disease (CHD) in Peru. Local control measures should focus primarily on decreasing dog and sheep infection rather than intermediate reservoirs.

Original language	American English
Pages (from-to)	89-92
Number of pages	4
Journal	American Journal of Tropical Medicine and Hygiene
Volume	79
Issue number	1
DOIs	https://doi.org/10.4269/ajtmh.2008.79.89
State	Indexed - Jul 2008
Externally published	Yes

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Santivañez, S. J., Gutierrez, A. M., Rosenzvit, M. C., Muzulin, P. M., Rodriguez, M. L., Vasquez, J. C., Rodriguez, S., Gonzalez, A. E., Gilman, R. H., & Garcia, H. H. (2008). Human hydatid disease in Peru is basically restricted to Echinococcus granulosus genotype G1. American Journal of Tropical Medicine and Hygiene, 79(1), 89-92. https://doi.org/10.4269/ajtmh.2008.79.89

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title = "Human hydatid disease in Peru is basically restricted to Echinococcus granulosus genotype G1",

abstract = "A molecular PCR study using DNA from 21 hydatid cysts was performed to determine which strain type is responsible for human infection in Peru. The mitochondrial cytochrome c oxidase subunit 1 (CO1) gene was amplified in 20 out of 21 samples, revealing that all but 1 sample (19/20, 95%) belonged to the common sheep strain (G1). The remaining samples belonged to the camel strain (G6). The G1 genotype was most frequently found in human cases of cystic hydatid disease (CHD) in Peru. Local control measures should focus primarily on decreasing dog and sheep infection rather than intermediate reservoirs.",

author = "Santiva{\~n}ez, {Saul J.} and Gutierrez, {Ariana M.} and Rosenzvit, {Mara C.} and Muzulin, {Patricia M.} and Rodriguez, {Mary L.} and Vasquez, {Julio C.} and Silvia Rodriguez and Gonzalez, {Armando E.} and Gilman, {Robert H.} and Garcia, {Hector H.}",

year = "2008",

month = jul,

doi = "10.4269/ajtmh.2008.79.89",

language = "American English",

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AU - Santivañez, Saul J.

AU - Gutierrez, Ariana M.

AU - Rosenzvit, Mara C.

AU - Muzulin, Patricia M.

AU - Rodriguez, Mary L.

AU - Vasquez, Julio C.

AU - Rodriguez, Silvia

AU - Gonzalez, Armando E.

AU - Gilman, Robert H.

AU - Garcia, Hector H.

PY - 2008/7

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AB - A molecular PCR study using DNA from 21 hydatid cysts was performed to determine which strain type is responsible for human infection in Peru. The mitochondrial cytochrome c oxidase subunit 1 (CO1) gene was amplified in 20 out of 21 samples, revealing that all but 1 sample (19/20, 95%) belonged to the common sheep strain (G1). The remaining samples belonged to the camel strain (G6). The G1 genotype was most frequently found in human cases of cystic hydatid disease (CHD) in Peru. Local control measures should focus primarily on decreasing dog and sheep infection rather than intermediate reservoirs.

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JO - American Journal of Tropical Medicine and Hygiene

JF - American Journal of Tropical Medicine and Hygiene

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Human hydatid disease in Peru is basically restricted to Echinococcus granulosus genotype G1

Abstract

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