Factores asociados a la variación de valores espirométricos en trabajadores a gran altura

Translated title of the contribution: Factors associated with variation in spirometric values in workers at high altitude

Christian R. Mejia, Matlin M. Cárdenas, Onice J. Cáceres, Araseli Verastegui-Diaz, Claudia A. Vera, Raúl Gomero-Cuadra

Research output: Contribution to journalOriginal Articlepeer-review

1 Scopus citations


Objective: To determine the temporal variation in spirometric values according to the geographical altitude of labor location on a group of mining workers. Material and methods: A longitudinal study using spirometry values of workers taken several years at two locations, one at sea level and another at high altitude in the Peruvian highlands. The values of forced expiratory volume in one second (FEV1), forced vital capacity (FVC) and Tiffeneau index (FEV1/FVC) were used. It were analyzed with models that adjust for time (PA-GEE), with Gaussian family, identity link function and robust models, the time variable was the year of spirometry take. P value and coefficients were used in each case. Results: From 1349 records, 86% (1162) were male, the median age was 35 years (interquartile range: 22-66). In multivariate analysis we found that there was a variation in the values of FEV1 and FVC, these increased in men, among those with greater stature and operators, but decreased with increasing age of the worker. The Tiffeneau index decreased only according to age of the worker, adjusted for all variables. Conclusions: According to these data, the change in spirometric values is influenced by the socio-anthropometric variables and the type of work they do. This must be applied for monitoring of employees who are exposed to similar conditions, as part of occupational surveillance programs.

Translated title of the contributionFactors associated with variation in spirometric values in workers at high altitude
Original languageSpanish
Pages (from-to)34-41
Number of pages8
JournalRevista de la Asociacion Espanola de Especialistas en Medicina del Trabajo
Issue number1
StateIndexed - 2020
Externally publishedYes

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