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Effect of minimal intervention on carious lesions in primary teeth. An Umbrella review

  • Tania Carola Padilla-Cáceres
  • , Heber Isac Arbildo-Vega
  • , Vilma Mamani-Cori
  • , Luz Marina Caballero-Apaza
  • , Fredy Hugo Cruzado-Oliva
  • , Carlos Alberto Farje-Gallardo
  • , Consuelo Marroquín-Soto
  • , Rubén Aguirre-Ipenza
  • , Hernán Vásquez-Rodrigo
  • , Sara Antonieta Luján-Valencia
  • , Joan Manuel Meza-Málaga
  • , Tania Belú Castillo-Cornock
  • , Franz Tito Coronel-Zubiate

Research output: Contribution to journalReview articlepeer-review

Abstract

Aim: To assess the effect of minimal intervention on carious lesions in primary teeth through an umbrella review. Material and methods: A comprehensive search was conducted in databases such as PubMed, Cochrane Library, Scopus, Web of Science, Embase, SciELO, Google Scholar, ProQuest Dissertations and Theses, and OpenGrey, covering literature up to September 2025. Systematic reviews, with or without meta-analyses, that assessed the effect of minimal intervention on carious lesions in primary teeth were included. Narrative reviews, rapid reviews, clinical trials, observational or experimental studies, case reports, editorials, letters, protocols, and posters were excluded. The methodological quality of the reviews was assessed using the AMSTAR-2 tool, and the risk of bias was assessed using the ROBIS tool. Results: From an initial retrieval of 498 records, 49 systematic reviews met the inclusion criteria. The data showed an impact of minimally invasive interventions on carious lesions in primary teeth. Conclusion: Based on high-confidence systematic reviews, among the minimally invasive interventions, the use of silver diamine fluoride, the Hall technique, and resin infiltration showed significant benefits for managing carious lesions in primary teeth. Systematic Review Registration: https://doi.org/10.17605/OSF.IO/3T2GV, Open Science Framework (OSF): doi: 10.17605/OSF.IO/3T2GV

Original languageAmerican English
Article number1751752
JournalFrontiers in Dental Medicine
Volume6
DOIs
StateIndexed - 2026

Bibliographical note

Publisher Copyright:
2026 Padilla-Cáceres, Arbildo-Vega, Mamani-Cori, Caballero-Apaza, Cruzado-Oliva, Farje-Gallardo, Marroquín-Soto, Aguirre-Ipenza, Vásquez-Rodrigo, Luján-Valencia, Meza-Málaga, Castillo-Cornock and Coronel-Zubiate.

Keywords

  • children
  • cognition
  • cognitive development
  • iron supplement
  • review

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