Case Report: Late onset of generalized isomorphic morphea in a postmenopausal woman

Marie Angelique Lazo-Betetta; Renzo Perez-Vasquez; Arantxa Sanchez-Boluarte; Fiorella Inga-Berrospi; J. Antonio Grandez-Urbina

doi:10.12688/f1000research.21610.1

Case Report: Late onset of generalized isomorphic morphea in a postmenopausal woman

Marie Angelique Lazo-Betetta, Renzo Perez-Vasquez, Arantxa Sanchez-Boluarte, Fiorella Inga-Berrospi, J. Antonio Grandez-Urbina

Faculty of health sciences

Research output: Contribution to journal › Original Article › peer-review

Abstract

Morphea is an inflammatory, sclerosing skin condition of unknown cause that generally does not present systemic manifestations. A 66-year-old Caucasian Peruvian female patient, who was previously a nurse, presented with a prior history of 4 years of indurated dermal plaque lesions with constant progression. Diagnosis of morphea was made by clinical examination and skin biopsy. The patient started topical treatment with methoxsalen and phototherapy. When no improvement was seen, it was switched to methotrexate. However, due to changes in liver profile, phototherapy was restarted with progressive clinical improvement. It is essential to differentiate all morphea subtypes for proper management.

Original language	American English
Article number	107
Journal	F1000Research
Volume	9
DOIs	https://doi.org/10.12688/f1000research.21610.1
State	Indexed - 2020

Bibliographical note

Funding Information:
The author(s) declared that no grants were involved in supporting this work.

Publisher Copyright:
Copyright: © 2020 Lazo-Betetta MA et al.

Keywords

Isomorphic generalized morphea; indurated plaque; postmenopausal woman

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10.12688/f1000research.21610.1

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title = "Case Report: Late onset of generalized isomorphic morphea in a postmenopausal woman",

abstract = "Morphea is an inflammatory, sclerosing skin condition of unknown cause that generally does not present systemic manifestations. A 66-year-old Caucasian Peruvian female patient, who was previously a nurse, presented with a prior history of 4 years of indurated dermal plaque lesions with constant progression. Diagnosis of morphea was made by clinical examination and skin biopsy. The patient started topical treatment with methoxsalen and phototherapy. When no improvement was seen, it was switched to methotrexate. However, due to changes in liver profile, phototherapy was restarted with progressive clinical improvement. It is essential to differentiate all morphea subtypes for proper management.",

keywords = "Isomorphic generalized morphea; indurated plaque; postmenopausal woman",

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note = "Funding Information: The author(s) declared that no grants were involved in supporting this work. Publisher Copyright: Copyright: {\textcopyright} 2020 Lazo-Betetta MA et al.",

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language = "American English",

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T2 - Late onset of generalized isomorphic morphea in a postmenopausal woman

AU - Lazo-Betetta, Marie Angelique

AU - Perez-Vasquez, Renzo

AU - Sanchez-Boluarte, Arantxa

AU - Inga-Berrospi, Fiorella

AU - Grandez-Urbina, J. Antonio

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N2 - Morphea is an inflammatory, sclerosing skin condition of unknown cause that generally does not present systemic manifestations. A 66-year-old Caucasian Peruvian female patient, who was previously a nurse, presented with a prior history of 4 years of indurated dermal plaque lesions with constant progression. Diagnosis of morphea was made by clinical examination and skin biopsy. The patient started topical treatment with methoxsalen and phototherapy. When no improvement was seen, it was switched to methotrexate. However, due to changes in liver profile, phototherapy was restarted with progressive clinical improvement. It is essential to differentiate all morphea subtypes for proper management.

AB - Morphea is an inflammatory, sclerosing skin condition of unknown cause that generally does not present systemic manifestations. A 66-year-old Caucasian Peruvian female patient, who was previously a nurse, presented with a prior history of 4 years of indurated dermal plaque lesions with constant progression. Diagnosis of morphea was made by clinical examination and skin biopsy. The patient started topical treatment with methoxsalen and phototherapy. When no improvement was seen, it was switched to methotrexate. However, due to changes in liver profile, phototherapy was restarted with progressive clinical improvement. It is essential to differentiate all morphea subtypes for proper management.

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M3 - Original Article

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SN - 2046-1402

VL - 9

JO - F1000Research

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ER -

Case Report: Late onset of generalized isomorphic morphea in a postmenopausal woman

Abstract

Bibliographical note

Keywords

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